Genetics and Periodontal Diseases

Description

Periodontal disease includes a broad spectrum of inflammatory and destructive responses to oral microbes in the susceptible human host.The genetic disorders are not the cause of the disease, they are the amplifiers of the disease process. Evidence for genetic influence on periodontitis comes from multiple sources including familial aggregation and formal genetic studies of aggressive forms of periodontitis and twin studies of chronic periodontitis. Reports of genetic polymorphisms associated with periodontal disease are increasing,in this context, a brief review has been prepared to enlighten the readers about the various aspects of genetics which are being used in the field of Periodontics. The scenario of various case control studies and literature in the past to date in order to to provide a brief overview of basic genetic concepts, genetic polymorphisms and to discuss the genetic aspects of various forms of periodontal diseases